Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421466 | 1.00 | POLB (0.45) | POLBMEN1KMT2AKDM4EEBP | |
| SCHEMBL6993906 | 1.00 | POLB (0.45) | POLBMEN1KMT2AKDM4EEBP | |
| SCHEMBL8420261 | 1.00 | POLB (0.45) | POLBMEN1KMT2AKDM4EEBP | |
| SCHEMBL1701604 | 0.83 | POLB (0.49) | POLBMEN1KMT2AKDM4EEBP | |
| SCHEMBL15438887 | 0.83 | POLB (0.49) | POLBMEN1KMT2AKDM4EEBP | |
| SCHEMBL7342618 | 0.83 | POLB (0.45) | POLBMEN1KMT2AKDM4EEBP | |
| SCHEMBL15447586 | 0.83 | POLB (0.49) | POLBMEN1KMT2AKDM4EEBP | |
| SCHEMBL7289985 | 0.83 | POLB (0.49) | POLBMEN1KMT2AKDM4EEBP | |
| SCHEMBL8406208 | 0.83 | POLB (0.49) | POLBMEN1KMT2AKDM4EEBP | |
| SCHEMBL23182281 | 0.82 | POLB (0.35) | POLBMEN1KMT2AKDM4EEBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585682-B1 | Process for the preparation of 2,6-dimethylmorpholine from N-(2-hydroxypropyl)-2,6-dimethylmorpholine | BASF AG (DE) | 1999-10-06 | — | — | EP | disclosed |
| US-5436335-A | Catalytic dealkylation using group Ib, IIb and group VIII metals | BASF AKTIENGESELLSCHAFT (DE) | 1995-07-25 | — | — | US | disclosed |
| EP-0585682-A2 | Process for the preparation of 2,6-dimethylmorpholine from N-(2-hydroxypropyl)-2,6-dimethylmorpholine | BASF Aktiengesellschaft (DE) | 1994-03-09 | — | — | EP | disclosed |