Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422049 | 0.83 | FDFT1 (0.40) | FDFT1 | |
| SCHEMBL8422019 | 0.82 | FDFT1 (0.36) | FDFT1 | |
| SCHEMBL8520997 | 0.81 | FDFT1 (0.39) | FDFT1 | |
| SCHEMBL8420062 | 0.81 | FDFT1 (0.47) | FDFT1 | |
| SCHEMBL8417909 | 0.80 | FDFT1 (0.38) | FDFT1 | |
| SCHEMBL8421874 | 0.80 | FDFT1 (0.39) | FDFT1 | |
| SCHEMBL8417676 | 0.80 | FDFT1 (0.44) | FDFT1KDM4EALDH1A1MAPK1 | |
| SCHEMBL8419593 | 0.79 | FDFT1 (0.49) | FDFT1ALDH1A1MAPK1 | |
| SCHEMBL8420483 | 0.79 | UGCG (0.35) | — | |
| SCHEMBL8417805 | 0.79 | FDFT1 (0.35) | FDFT1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |