Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NAT1 | P18440 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422911 | 0.92 | KDM1A (0.41) | KDM1AAURKAMAOAMALT1MAPT | |
| SCHEMBL8421767 | 0.91 | MALT1 (0.39) | KDM1AAURKAMAOAMALT1MAPT | |
| SCHEMBL8420855 | 0.88 | KDM1A (0.40) | KDM1AAURKAMALT1MAPTCYP3A4 | |
| SCHEMBL8420731 | 0.88 | KDM1A (0.43) | KDM1AAURKAMAOAMALT1MAPT | |
| SCHEMBL8422266 | 0.88 | KDM1A (0.43) | KDM1AAURKAMAOAMALT1MAPT | |
| SCHEMBL8421656 | 0.87 | KDM1A (0.42) | KDM1AAURKAMAOAMALT1MAPT | |
| SCHEMBL8420739 | 0.87 | MALT1 (0.40) | KDM1AAURKAMAOAMALT1MAPT | |
| SCHEMBL8422316 | 0.86 | KDM1A (0.44) | KDM1AAURKAMAOAMALT1MAPT | |
| SCHEMBL8421776 | 0.86 | KDM1A (0.47) | KDM1AAURKAMAOAMALT1MAPT | |
| SCHEMBL8424102 | 0.86 | KDM1A (0.40) | KDM1AAURKAMAOAMALT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |