SCHEMBL8423769

SCHEMBL8423769

O=[C]C(F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8662742 0.73
SCHEMBL27921396 0.71
SCHEMBL4863301 0.71
SCHEMBL933506 0.67
Apaflurane SCHEMBL9159453 0.67
SCHEMBL11825650 0.67
SCHEMBL7706944 0.67
SCHEMBL1089961 0.66
SCHEMBL5439 0.66
SCHEMBL8933099 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0694526-B1 Process for preparation of fluorinated beta-keto ester ROHM & HAAS (US) 1998-10-07 EP claimed
US-11028386-B2 Morpholino oligonucleotide manufacturing method AJINOMOTO CO., INC. (JP) 2021-06-08 US disclosed
CN-112159322-A Auxiliary monomer for modified polyacrylate and modified polyacrylate 杭州师范大学 2021-01-01 CN disclosed
US-20200040331-A1 MORPHOLINO OLIGONUCLEOTIDE MANUFACTURING METHOD AJINOMOTO CO., INC. (JP) 2020-02-06 US disclosed
US-10472624-B2 Morpholino oligonucleotide manufacturing method AJINOMOTO CO., INC. (JP) 2019-11-12 US disclosed
US-10415036-B2 Morpholino oligonucleotide manufacturing method AJINOMOTO CO., INC. (JP) 2019-09-17 US disclosed
US-20180016580-A1 MORPHOLINO OLIGONUCLEOTIDE MANUFACTURING METHOD AJINOMOTO CO., INC. (JP) 2018-01-18 US disclosed
US-9790497-B2 Morpholino oligonucleotide manufacturing method AJINOMOTO CO., INC. (JP) 2017-10-17 US disclosed
EP-3208277-A1 MORPHOLINO OLIGONUCLEOTIDE MANUFACTURING METHOD AJINOMOTO CO., INC. (JP) 2017-08-23 EP disclosed
US-20170218361-A1 MORPHOLINO OLIGONUCLEOTIDE MANUFACTURING METHOD AJINOMOTO CO., INC. (JP) 2017-08-03 US disclosed
EP-3015467-A1 MORPHOLINO OLIGONUCLEOTIDE MANUFACTURING METHOD Ajinomoto Co., Inc. (JP) 2016-05-04 EP disclosed
US-20160076033-A1 MORPHOLINO OLIGONUCLEOTIDE MANUFACTURING METHOD AJINOMOTO CO., INC. (JP) 2016-03-17 US disclosed
EP-0636616-B1 Process for production of fluoroalkanecarboxamide derivatives SUMITOMO CHEMICAL CO (JP) 1999-10-27 EP disclosed
US-5484933-A Process for production of fluoroalkane carboxamide derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-01-16 US disclosed
EP-0636616-A1 Process for production of fluoroalkanecarboxamide derivatives SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-02-01 EP disclosed