Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 3/20 | 0.45 |
| ▸ | F10 | P00742 | 12/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | PROC | P04070 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423730 | 0.93 | F10 (0.49) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8425505 | 0.91 | F10 (0.45) | F10TP53POLBF2CNR1 | |
| SCHEMBL8424224 | 0.90 | GAA (0.41) | BDKRB1F10PLGPROCTP53 | |
| SCHEMBL8428300 | 0.89 | F10 (0.48) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8425504 | 0.89 | F10 (0.47) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8423392 | 0.87 | F10 (0.47) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8428321 | 0.86 | F10 (0.50) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8425339 | 0.85 | F10 (0.46) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8425519 | 0.84 | F10 (0.51) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8427943 | 0.83 | F10 (0.49) | F10PLGPROCF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |