⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595620 | 0.77 | TP53 (0.32) | — | |
| SCHEMBL21044988 | 0.76 | TP53 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7205877 | 0.75 | KDM4E (0.31) | — | |
| SCHEMBL28465794 | 0.73 | TAAR1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL8380429 | 0.73 | AGXT (0.33) | — | |
| SCHEMBL28474300 | 0.73 | — | — | |
| Bromide SCHEMBL8380336 | 0.73 | IDO1 (0.31) | — | |
| SCHEMBL28465804 | 0.73 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL7174568 | 0.72 | — | — | |
| SCHEMBL7594556 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886117-A | Process using borane derived catalysts for preparation of syndiotactic vinyl aromatic polymers | THE DOW CHEMICAL COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0742226-B1 | Process for preparing borane derived catalysts for preparation of syndiotactic vinyl aromatic polymers | DOW CHEMICAL CO (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0742226-A2 | Process for preparing borane derived catalysts for preparation of syndiotactic vinyl aromatic polymers | THE DOW CHEMICAL COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| EP-0421659-B1 | Process for preparation of syndiotactic vinyl aromatic polymers | DOW CHEMICAL CO (US) | 1996-07-10 | — | — | EP | disclosed |
| US-5206197-A | CATALYST COMPOSITION FOR PREPARATION OF SYNDIOTACTIC VINYL AROMATIC POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1993-04-27 | — | — | US | disclosed |
| US-5066741-A | Contacting monomers with complex catalyst | THE DOW CHEMICAL COMPANY (US) | 1991-11-19 | — | — | US | disclosed |