Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.46 |
| ▸ | F2 | P00734 | 11/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PROC | P04070 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425582 | 0.89 | F10 (0.45) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8427973 | 0.88 | KDM2B (0.44) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8424801 | 0.88 | KDM2B (0.44) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8425579 | 0.87 | F10 (0.48) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8425520 | 0.86 | F10 (0.47) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8427975 | 0.86 | F10 (0.47) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8424800 | 0.86 | F10 (0.47) | F10F2PLGPROCPRSS1 | |
| SCHEMBL2326662 | 0.77 | F10 (0.72) | F10F2PLGPROCPRSS1 | |
| SCHEMBL2331939 | 0.77 | F10 (0.72) | F10F2PLGPROCPRSS1 | |
| SCHEMBL2329385 | 0.77 | F10 (0.71) | F10F2PLGPROCPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |