Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424980 | 1.00 | KDM4E (0.61) | KDM4EGAAMAPTLMNATHRB | |
| SCHEMBL8424978 | 1.00 | KDM4E (0.61) | KDM4EGAAMAPTLMNATHRB | |
| SCHEMBL10465349 | 0.90 | KDM4E (0.64) | KDM4EGAAMAPTLMNATHRB | |
| SCHEMBL10464274 | 0.90 | KDM4E (0.64) | KDM4EGAAMAPTLMNATHRB | |
| SCHEMBL10464276 | 0.90 | KDM4E (0.64) | KDM4EGAAMAPTLMNATHRB | |
| SCHEMBL11312156 | 0.84 | MAPT (0.61) | KDM4EGAAMAPTLMNATHRB | |
| SCHEMBL10741104 | 0.84 | MAPT (0.61) | KDM4EGAAMAPTLMNATHRB | |
| SCHEMBL10741098 | 0.84 | MAPT (0.61) | KDM4EGAAMAPTLMNATHRB | |
| Acetic Acid SCHEMBL10426738 | 0.83 | MAPT (0.59) | KDM4EGAAMAPTLMNATHRB | |
| SCHEMBL7822895 | 0.82 | KDM4E (0.56) | KDM4EMAPTAPPKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990318-A | Soluble polyester-supported chiral phosphines | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 1999-11-23 | — | — | US | claimed |
| US-5990318-A | Soluble polyester-supported chiral phosphines | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 1999-11-23 | — | — | US | disclosed |
| US-4294989-A | OPTICALLY ACTIVE HYDROGENATION CATALYSTS | MONSANTO COMPANY (US) | 1981-10-13 | — | — | US | disclosed |
| US-4265827-A | METHYLCYCOHEXYL-O-ANISYLARSINE OPTICALLY ACTIVE CATALYST | MONSANTO COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| US-4261919-A | OF BETA-SUBSTITUTED-ALPHA-ACYLAMIDO-ACRYLIC ACIDS TO YIELD OPTICALLY ACTIVE MIXTURE | MONSANTO COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| US-4124533-A | HYDROGENATION CATALYSTS | MONSANTO COMPANY (US) | 1978-11-07 | — | — | US | disclosed |