Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267199 | 0.83 | HSD17B10 (0.51) | PTK2GAACYP1A2KMT2ATDP1 | |
| SCHEMBL31267203 | 0.83 | HSD17B10 (0.51) | PTK2GAACYP1A2KMT2ATDP1 | |
| SCHEMBL3306300 | 0.81 | PTK2 (0.59) | PTK2GAACYP1A2L3MBTL1KMT2A | |
| SCHEMBL2759546 | 0.81 | PTK2 (0.59) | PTK2GAACYP1A2L3MBTL1KMT2A | |
| SCHEMBL9455571 | 0.80 | PTK2 (0.62) | PTK2GAACYP1A2L3MBTL1KMT2A | |
| SCHEMBL2642701 | 0.80 | PTK2 (0.57) | PTK2GAACYP1A2L3MBTL1KMT2A | |
| SCHEMBL2642704 | 0.80 | PTK2 (0.57) | PTK2GAACYP1A2L3MBTL1KMT2A | |
| SCHEMBL4550164 | 0.80 | PTK2 (0.57) | PTK2GAACYP1A2L3MBTL1KMT2A | |
| SCHEMBL13369510 | 0.80 | PTK2 (0.57) | PTK2GAACYP1A2L3MBTL1KMT2A | |
| SCHEMBL3981252 | 0.79 | PTK2 (0.56) | PTK2GAACYP1A2L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001856-A | β-adrenergic agonists to reduce a wasting condition | PFIZER INC. (US) | 1999-12-14 | — | — | US | disclosed |