Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.63 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8425147 | 0.82 | ESR1 (0.72) | ESR1ESR2 | |
| SCHEMBL30076531 | 0.80 | ESR1 (0.89) | ESR1ESR2 | |
| SCHEMBL9247758 | 0.79 | ESR1 (0.69) | ESR1ESR2LTA4H | |
| SCHEMBL9153745 | 0.79 | ESR1 (0.98) | ESR1ESR2 | |
| SCHEMBL7941540 | 0.78 | ESR1 (0.71) | ESR1ESR2LTA4H | |
| SCHEMBL7943653 | 0.78 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL29362450 | 0.78 | ESR1 (0.69) | ESR1ESR2LTA4H | |
| SCHEMBL6669000 | 0.78 | ESR1 (0.69) | ESR1ESR2LTA4H | |
| Hydrochloric Acid SCHEMBL8429229 | 0.77 | ESR1 (0.98) | ESR1ESR2 | |
| SCHEMBL8489565 | 0.76 | ESR1 (0.55) | ESR1ESR2LTA4HKDM4EPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5980938-A | ADMINISTERING A DIBENZYL BENZOPYRANS | ELI LILLY AND COMPANY (US) | 1999-11-09 | — | — | US | disclosed |