Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.53 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | LAP3 | P28838 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14038058 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL8192972 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL27569923 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL2920941 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL6762998 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL28888696 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL27539628 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL18151772 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL27438801 | 0.98 | GRIK1 (0.52) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| Ammonia Solution, Strong SCHEMBL8469689 | 0.98 | GRIK1 (0.52) | GRIK1GRIK2GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1252040-C | Novel aryl, alkenyl and alkynl 4-dedimethylamino tetracycline derivatives | COLLAGENEX PHARM INC (US) | 2006-04-19 | — | — | CN | disclosed |
| CN-1056602-C | Esters and amides as PLA2 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-09-20 | — | — | CN | disclosed |
| US-5993823-A | BETWEEN 10 AND 40 AMINO ACIDS AND AT LEAST ONE ANTIGENIC DETERMINANT, ALSO COMPRISING A CHAIN FROM PIMELAUTIDE, TRIMEXAUTIDE, HEXADECANOIC ACID, 2-AMINO-HEXADECANOIC ACID, STEROID GROUPS AND DERIVATIVES THEREOF | INSTITUT PASTEUR DE LILLE (FR) | 1999-11-30 | — | — | US | disclosed |
| CN-1197450-A | Esters and amides as phospholipase A2 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-10-28 | — | — | CN | disclosed |
| EP-0253007-A1 | Stabilized polymers, novel stabilizers, and synthesis thereof | The B.F. GOODRICH Company (US) | 1988-01-20 | — | — | EP | disclosed |