Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.49 |
| ▸ | F2 | P00734 | 6/20 | 0.49 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PROC | P04070 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423852 | 0.90 | F10 (0.54) | F10F2KLK6PLGPROC | |
| SCHEMBL8424713 | 0.90 | F10 (0.50) | F10F2KLK6PLGPROC | |
| SCHEMBL8428321 | 0.89 | F10 (0.50) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8423753 | 0.85 | F10 (0.51) | F10F2KLK6PLGPROC | |
| SCHEMBL8428315 | 0.85 | F10 (0.48) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8428253 | 0.83 | F10 (0.49) | F10F2KLK6PLGPROC | |
| SCHEMBL8423730 | 0.83 | F10 (0.49) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8425519 | 0.82 | F10 (0.51) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8428300 | 0.82 | F10 (0.48) | F10F2PLGPROCPRSS1 | |
| SCHEMBL2332815 | 0.81 | KLK6 (0.56) | F10F2KLK6PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |