Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.55 |
| ▸ | F2 | P00734 | 6/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PROC | P04070 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425373 | 0.91 | F10 (0.52) | F10F2PRSS1PLGPROC | |
| SCHEMBL8427943 | 0.89 | F10 (0.49) | F10F2PRSS1PLGPROC | |
| SCHEMBL8425839 | 0.86 | F10 (0.55) | F10F2PRSS1PLGPROC | |
| SCHEMBL2326339 | 0.84 | F10 (0.74) | F10F2PRSS1PLGPROC | |
| SCHEMBL2333482 | 0.82 | F10 (0.57) | F10F2PRSS1PLGPROC | |
| SCHEMBL8423852 | 0.82 | F10 (0.54) | F10F2PRSS1PLGPROC | |
| SCHEMBL8428326 | 0.81 | F10 (0.61) | F10F2PRSS1PLGPROC | |
| SCHEMBL2330053 | 0.80 | F10 (0.68) | F10F2PLGPROC | |
| SCHEMBL8423629 | 0.80 | F10 (0.55) | F10F2PRSS1PLGPROC | |
| SCHEMBL8425659 | 0.80 | F10 (0.52) | F10F2PRSS1PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |