Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8425642

COc1ccc2ccc(S(=O)(=O)CNC3CCN(Cc4ccnc(C(=N)N)c4)C3=O)cc2c1.O=C(O)C(F)(F)F

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 0.72
F2 P00734 6/20 0.72
PLG P00747 1/20 0.55
PROC P04070 1/20 0.55
PRSS1 P07477 1/20 0.55
KLK6 Q92876 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL2335622 0.90 F10 (0.89) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2335620 0.90 F10 (0.89) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL8425346 0.87 F10 (0.72) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2329447 0.84 F10 (0.68) F10F2PLGPROCKLK6
Trifluoroacetic Acid SCHEMBL2329444 0.84 F10 (0.68) F10F2PLGPROCKLK6
Trifluoroacetic Acid SCHEMBL8428379 0.84 F10 (0.72) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL8425502 0.84 F10 (0.71) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2328211 0.84 F10 (0.64) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2328852 0.84 F10 (0.72) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2326426 0.83 F10 (0.70) F10F2PLGPROCKLK6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5958918-A Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds RHONE-POULENC RORER PHARMACEUTICALS INC. 1999-09-28 US claimed
US-5958918-A Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds RHONE-POULENC RORER PHARMACEUTICALS INC. 1999-09-28 US disclosed