SCHEMBL8425713

SCHEMBL8425713

Cc1cccc(COC(=O)c2ccccc2O)c1.[Zn]

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.68
MMP2 P08253 1/20 0.53
MMP9 P14780 1/20 0.53
MMP12 P39900 1/20 0.53
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
ALDH1A1 P00352 2/20 0.49
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48
STAT1 P42224 1/20 0.48
POLB P06746 1/20 0.47
TSHR P16473 2/20 0.46
LMNA P02545 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPK1 P28482 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10780057 0.99 TDP1 (0.69) TDP1MMP2MMP9MMP12KMT2A
Benzyl Salicylate SCHEMBL27731147 0.83 TDP1 (0.96) TDP1KMT2ARAB9AALDH1A1KDM4E
SCHEMBL27659738 0.82 TDP1 (0.76) TDP1MMP2MMP9MMP12KMT2A
SCHEMBL29514798 0.82 TDP1 (0.76) TDP1MMP2MMP9MMP12KMT2A
SCHEMBL8425730 0.82 HTT (0.56) MMP2MMP9MMP12KMT2AMEN1
Benzyl Salicylate SCHEMBL1871397 0.81 TDP1 (1.00) TDP1KMT2ARAB9AALDH1A1KDM4E
Benzyl Salicylate SCHEMBL30184766 0.81 TDP1 (1.00) TDP1KMT2ARAB9AALDH1A1KDM4E
Benzyl Salicylate SCHEMBL15573 0.81 TDP1 (1.00) TDP1KMT2ARAB9AALDH1A1KDM4E
SCHEMBL28346226 0.81 TDP1 (0.65) TDP1KMT2AMEN1RAB9AALDH1A1
Benzyl Salicylate SCHEMBL28184183 0.80 TDP1 (0.90) TDP1KMT2ARAB9AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0547629-B2 Color developers and sheets thereof SANYO CHEMICAL IND LTD (JP) 1999-10-27 EP disclosed
US-5382560-A Metal salt of styrene-salicyclic acid compound SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1995-01-17 US disclosed
EP-0547629-A1 Color developers and sheets thereof SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1993-06-23 EP disclosed