Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793712 | 0.89 | KMT2A (0.63) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL15238210 | 0.84 | HDAC3 (0.71) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL15238211 | 0.84 | HDAC3 (0.71) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL15238227 | 0.84 | HDAC3 (0.71) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL31036028 | 0.83 | HDAC1 (0.60) | HDAC1HDAC8ASAH1CYP1A2EPHX1 | |
| SCHEMBL31036034 | 0.83 | HDAC1 (0.60) | HDAC1HDAC8ASAH1CYP1A2EPHX1 | |
| SCHEMBL10658849 | 0.82 | HDAC3 (0.72) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL10110752 | 0.81 | HTT (0.54) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL7831694 | 0.80 | HDAC1 (0.60) | HDAC1HDAC8CYP1A2 | |
| SCHEMBL8422184 | 0.79 | HDAC1 (0.58) | HDAC1HDAC8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949238-A1 | SUBSTITUTED PROPIONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |