Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.37 |
| ▸ | F2 | P00734 | 9/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | PROC | P04070 | 1/20 | 0.37 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2332558 | 0.91 | F10 (0.46) | F10F2PLGPLATPROC | |
| SCHEMBL2332931 | 0.90 | F10 (0.44) | F10F2PLGPLATPROC | |
| SCHEMBL8424709 | 0.89 | F10 (0.42) | F10F2PLGPLATPROC | |
| SCHEMBL2329743 | 0.88 | F10 (0.46) | F10F2PLGPLATPROC | |
| SCHEMBL2327584 | 0.87 | F10 (0.40) | F10F2PLGPLATPROC | |
| SCHEMBL8425687 | 0.82 | MGAT2 (0.35) | F10F2PLGPROCENPP2 | |
| SCHEMBL8428420 | 0.81 | F10 (0.33) | F10F2ENPP2FNTAFNTB | |
| SCHEMBL2329425 | 0.80 | F10 (0.52) | F10F2PLGPLATPROC | |
| SCHEMBL2329089 | 0.79 | F10 (0.40) | F10F2PLGPLATPROC | |
| SCHEMBL8428258 | 0.79 | F10 (0.59) | F10F2PLGPLATPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |