Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428627 | 0.94 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7091626 | 0.92 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7088432 | 0.92 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8428633 | 0.92 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8426227 | 0.92 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8428683 | 0.91 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8428820 | 0.90 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8426361 | 0.88 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8426232 | 0.88 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8424408 | 0.87 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5928562-A | HAVING EXTENDED HYDROCARBON ETHER GROUP ADJACENT TO A TERMINAL FLUOROALKYL OR FLUOROETHER GROUP; LOW VISCOSITY; HIGH SPEED RESPONSE; BRIGHTNESS; COMMPATIBILITY; DISPLAYS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-07-27 | — | — | US | disclosed |