Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.59 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 4/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27931897 | 1.00 | SLC1A1 (0.59) | SLC1A1SLC1A3SLC1A2KMT2AMEN1 | |
| SCHEMBL8836944 | 1.00 | SLC1A1 (0.59) | SLC1A1SLC1A3SLC1A2KMT2AMEN1 | |
| SCHEMBL5286295 | 0.84 | SLC1A1 (0.54) | SLC1A1SLC1A3SLC1A2KMT2AMEN1 | |
| SCHEMBL21853773 | 0.84 | SLC1A1 (0.54) | SLC1A1SLC1A3SLC1A2KMT2AMEN1 | |
| SCHEMBL724210 | 0.82 | SLC1A1 (0.57) | SLC1A1SLC1A3SLC1A2KMT2AMEN1 | |
| SCHEMBL4382418 | 0.82 | CA1 (0.66) | SLC1A1KMT2ACA1CA2CA7 | |
| SCHEMBL93708 | 0.82 | CA1 (0.66) | SLC1A1KMT2ACA1CA2CA7 | |
| SCHEMBL93709 | 0.82 | CA1 (0.66) | SLC1A1KMT2ACA1CA2CA7 | |
| SCHEMBL4385964 | 0.82 | CA1 (0.66) | SLC1A1KMT2ACA1CA2CA7 | |
| SCHEMBL8836900 | 0.81 | SLC1A1 (0.51) | SLC1A1SLC1A3SLC1A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962660-A | COMPOUND WHICH SUPPRESSES SELECTIN-MEDIATED CELLULAR ADHESION; FOR STABLE ANTIINFLAMMATORY AGENTS WITH BETTER BIOAVAILABILITY AND GREATER ACTIVITY WHICH ARE EASIER TO SYNTHESIZE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-10-05 | — | — | US | disclosed |