Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2R | P11717 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | SELP | P16109 | 2/20 | 0.40 |
| ▸ | PYGB | P11216 | 1/20 | 0.40 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429255 | 1.00 | IGF2R (0.44) | IGF2RKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL2530868 | 1.00 | IGF2R (0.44) | IGF2RKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL10623070 | 1.00 | IGF2R (0.44) | IGF2RKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL8429129 | 1.00 | IGF2R (0.44) | IGF2RKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL9814457 | 1.00 | IGF2R (0.44) | IGF2RKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL8907380 | 1.00 | IGF2R (0.44) | IGF2RKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL10620442 | 1.00 | IGF2R (0.44) | IGF2RKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL8429127 | 1.00 | IGF2R (0.44) | IGF2RKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL8405222 | 1.00 | IGF2R (0.44) | IGF2RKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL28179834 | 0.93 | IGF2R (0.46) | IGF2RSELPPYGBLGALS9LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953357-A1 | NEPHROTROPIC DRUGS | Drug Delivery System Institute, Ltd. (JP) | 1999-11-03 | — | — | EP | disclosed |