Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 17/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129752 | 0.89 | ADRB3 (0.65) | ADRB3ADRB1ALOX15ADRB2 | |
| SCHEMBL8477150 | 0.89 | ADRB3 (0.65) | ADRB3ADRB1ALOX15ADRB2 | |
| SCHEMBL8477156 | 0.89 | ADRB3 (0.65) | ADRB3ADRB1ALOX15ADRB2 | |
| SCHEMBL8480309 | 0.86 | ADRB3 (0.61) | ADRB3ADRB1ALOX15ADRB2 | |
| SCHEMBL8480316 | 0.86 | ADRB3 (0.61) | ADRB3ADRB1ALOX15ADRB2 | |
| SCHEMBL8480311 | 0.86 | ADRB3 (0.61) | ADRB3ADRB1ALOX15ADRB2 | |
| SCHEMBL3704286 | 0.85 | ADRB3 (0.60) | ADRB3ADRB1ALOX15ADRB2 | |
| SCHEMBL3704284 | 0.85 | ADRB3 (0.60) | ADRB3ADRB1ALOX15ADRB2 | |
| SCHEMBL3511598 | 0.85 | ADRB3 (0.65) | ADRB3ADRB1ALOX15ADRB2 | |
| SCHEMBL3157183 | 0.85 | ADRB3 (0.65) | ADRB3ADRB1ALOX15ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0887079-A1 | Beta-Adrenergic agonists to reduce a wasting condition | PFIZER INC. (US) | 1998-12-30 | — | — | EP | claimed |
| US-6001856-A | β-adrenergic agonists to reduce a wasting condition | PFIZER INC. (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0887079-A1 | Beta-Adrenergic agonists to reduce a wasting condition | PFIZER INC. (US) | 1998-12-30 | — | — | EP | disclosed |