Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | S100A9 | P06702 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2654048 | 0.89 | TSHR (0.44) | IDO1TSHRERN1DAO | |
| SCHEMBL2336642 | 0.84 | IDO1 (0.41) | IDO1ERN1 | |
| SCHEMBL114694 | 0.75 | — | — | |
| SCHEMBL29999249 | 0.75 | TSHR (0.40) | IDO1TSHR | |
| SCHEMBL3983596 | 0.75 | TSHR (0.40) | IDO1TSHR | |
| SCHEMBL28894230 | 0.75 | TSHR (0.40) | IDO1TSHR | |
| SCHEMBL20242292 | 0.74 | TACR1 (0.38) | IDO1ERN1 | |
| SCHEMBL4780801 | 0.74 | ERN1 (0.36) | IDO1TSHRERN1 | |
| SCHEMBL3396094 | 0.74 | AKR1B1 (0.33) | IDO1 | |
| SCHEMBL1160984 | 0.74 | DAO (0.39) | IDO1ERN1DAOS100A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693467-B | Thiazole amine MBL inhibitor and preparation method and application thereof | 四川大学 | 2025-02-14 | — | — | CN | disclosed |
| CN-116693467-A | Thiazole amine MBL inhibitor and preparation method and application thereof | 四川大学 | 2023-09-05 | — | — | CN | disclosed |
| WO-2023160582-A1 | THIAZOLAMINE MBL INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川大学 | 2023-08-31 | — | — | WO | disclosed |
| US-5945382-A | AND A METHOD OF THEIR PREPARATION BY CHLORINATION OF AN INTERMEDIATE ARYLPYRAZOLE; PROTECTION AGAINST FUNGAL DISEASES IN TOMATO, RICE, AND WHEAT PLANTS | RHONE-POULENC AGROCHIMIE (FR) | 1999-08-31 | — | — | US | disclosed |