Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | USP10 | Q14694 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3126932 | 0.90 | KMT2A (0.62) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL3126940 | 0.90 | KMT2A (0.62) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL13520164 | 0.84 | KMT2A (0.56) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL3598047 | 0.83 | KMT2A (0.61) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL3071975 | 0.82 | KMT2A (0.57) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL3601937 | 0.82 | KMT2A (0.57) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL1981486 | 0.77 | KMT2A (0.67) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL3500828 | 0.77 | KMT2A (0.51) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL3500826 | 0.77 | KMT2A (0.51) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL2965278 | 0.76 | KMT2A (0.65) | KMT2AALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880147-A | Amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prohylactic use | SANKYO COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |