Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pantothenic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | VNN1 | O95497 | 13/20 | 0.57 |
| ▸ | ECE1 | P42892 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pantothenic Acid SCHEMBL29506778 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1ECE1 | |
| Pantothenic Acid SCHEMBL19031708 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1ECE1 | |
| Pantothenic Acid, Racemic SCHEMBL27577879 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1ECE1 | |
| Pantothenic Acid, Racemic SCHEMBL28456165 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1ECE1 | |
| Pantothenic Acid SCHEMBL27903324 | 0.97 | PTGS1 (0.65) | PTGS1KCNH2VNN1ECE1 | |
| Pantothenic Acid SCHEMBL124922 | 0.97 | PTGS1 (0.65) | PTGS1KCNH2VNN1ECE1 | |
| Pantothenic Acid SCHEMBL8506535 | 0.97 | PTGS1 (0.65) | PTGS1KCNH2VNN1ECE1 | |
| Pantothenic Acid, Racemic SCHEMBL9113975 | 0.95 | PTGS1 (0.63) | PTGS1KCNH2VNN1ECE1 | |
| Pantothenic Acid SCHEMBL5295620 | 0.95 | PTGS1 (0.63) | PTGS1KCNH2VNN1ECE1 | |
| Pantothenic Acid SCHEMBL5436 | 0.95 | PTGS1 (0.67) | PTGS1KCNH2VNN1ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968788-A | CULTURING CANDIDA FAMATA, CANDIDA GUILLIERMONDII, YARROWIA LIPOLYTICA, PICHIA GLUCOZYMA, OR SACCHAROMYCES CEREVISIAE IN MEDIUM WITH GLUCOSE, FRUCTOSE, SUCROSE, OR MALTOSE; RECOVERING AT LEAST 0.3 MILLIGRAMS FOLIC ACID PER LITER MEDIA | TORAY INDUSTRIES, INC. (JP) | 1999-10-19 | — | — | US | disclosed |