Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21644363 | 0.94 | CYP4F2 (0.46) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 | |
| SCHEMBL20481347 | 0.90 | CYP4F2 (0.52) | CYP4F2CYP4A11USP2SMN1; SMN2TDP1 | |
| SCHEMBL20487757 | 0.90 | CYP4F2 (0.52) | CYP4F2CYP4A11USP2SMN1; SMN2TDP1 | |
| SCHEMBL1744071 | 0.88 | USP2 (0.46) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 | |
| SCHEMBL20812730 | 0.84 | CYP4F2 (0.54) | CYP4F2CYP4A11USP2SMN1; SMN2TDP1 | |
| SCHEMBL22284343 | 0.83 | CYP4F2 (0.52) | CYP4F2CYP4A11USP2SMN1; SMN2TDP1 | |
| SCHEMBL321594 | 0.82 | USP2 (0.49) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 | |
| SCHEMBL10172533 | 0.81 | USP2 (0.50) | USP2SMN1; SMN2NR1H2HPGDEPHX2 | |
| SCHEMBL23579455 | 0.80 | CYP4F2 (0.43) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 | |
| SCHEMBL21565392 | 0.80 | CYP4F2 (0.58) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973156-A | Piperidine and tetrahydropyridine derivatives | MERCK SHARP & DOME LTD. (GB) | 1999-10-26 | — | — | US | disclosed |