Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430231 | 1.00 | MEN1 (0.58) | MEN1ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL7824305 | 0.87 | MEN1 (0.64) | MEN1ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL7824299 | 0.87 | MEN1 (0.64) | MEN1ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL7835457 | 0.87 | MEN1 (0.64) | MEN1ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL7835462 | 0.87 | MEN1 (0.64) | MEN1ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL8433327 | 0.83 | MEN1 (0.64) | MEN1ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL8433315 | 0.83 | MEN1 (0.64) | MEN1ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL8430196 | 0.78 | MAPT (0.69) | MEN1ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL8430192 | 0.78 | MAPT (0.69) | MEN1ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL4034048 | 0.77 | TNFRSF1A (0.53) | TNFRSF1APTPN1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952355-A | 1-ETHER-SUBSTITUTED PHENYL-3-INDOL-3-YL-2-PROPEN-1-ONE DERIVATIVES; ANTITUMOR AND -CARCINOGENIC AGENTS; IMMUNOSUPPRESSANTS; AUTOIMMUNE DISEASES; SIDE EFFECT REDUCTION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0770601-A1 | PROPENONE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |