Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | CES1 | P23141 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28717818 | 0.89 | TDP1 (0.43) | TSHRFAAHALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9295757 | 0.87 | KMT2A (0.54) | TSHRFAAHMAPTKMT2AALDH1A1 | |
| SCHEMBL3632919 | 0.87 | KMT2A (0.54) | TSHRFAAHMAPTKMT2AALDH1A1 | |
| SCHEMBL11796286 | 0.87 | KMT2A (0.54) | TSHRFAAHMAPTKMT2AALDH1A1 | |
| SCHEMBL11795366 | 0.87 | KMT2A (0.54) | TSHRFAAHMAPTKMT2AALDH1A1 | |
| SCHEMBL3131865 | 0.87 | KMT2A (0.54) | TSHRFAAHMAPTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3634285 | 0.85 | KMT2A (0.52) | TSHRFAAHMAPTKMT2AALDH1A1 | |
| SCHEMBL176299 | 0.84 | TSHR (0.50) | TSHRFAAHMAPTKMT2AALDH1A1 | |
| SCHEMBL9539734 | 0.83 | TSHR (0.48) | TSHRFAAHMAPTKMT2AALDH1A1 | |
| SCHEMBL515245 | 0.83 | MAPT (0.59) | TSHRFAAHMAPTABCC4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201905-A | Cationic lipid | 武田药品工业株式会社 | 2024-06-14 | — | — | CN | disclosed |
| US-5910590-A | INTERACTS WITH GABA BINDING SITE (THE BENZODIAZEPINE RECEPTOR); TREATMENT OF ANXIETY, SEIZURE AND SLEEP DISORDERS, ENHANCES ALERTNESS AND TREATMENT OF BENZODIAZEPINE OVERDOSES | NEUROGEN CORPORATION (US) | 1999-06-08 | — | — | US | disclosed |