SCHEMBL8430233

SCHEMBL8430233

COC(=O)c1cc(Cl)ccc1NSC(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.48
NR4A2 P43354 2/20 0.43
PDK2 Q15119 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
RXFP1 Q9HBX9 2/20 0.42
KCNK2 O95069 1/20 0.41
KCNK10 P57789 1/20 0.41
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 2/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
HSD17B10 Q99714 1/20 0.40
HTT P42858 1/20 0.39
PDK1 Q15118 1/20 0.39
PDK3 Q15120 1/20 0.39
PDK4 Q16654 1/20 0.39
CFTR P13569 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15635249 0.77 ABL1 (0.48) ABL1NR4A2PDK2MEN1KMT2A
SCHEMBL4358899 0.77 KDM4E (0.67) ABL1NR4A2MEN1KMT2ASLC6A4
SCHEMBL27241 0.76 ABL1 (0.47) ABL1NR4A2MEN1KMT2AHTT
SCHEMBL8426070 0.75 ABL1 (0.46) ABL1NR4A2PDK2MEN1KMT2A
SCHEMBL5928677 0.74 KDM4E (0.71) ABL1NR4A2MEN1KMT2ASLC6A4
SCHEMBL4365379 0.74 ABL1 (0.54) ABL1NR4A2PDK2SLC6A4SLC6A3
SCHEMBL1462096 0.73 ABL1 (0.61) ABL1NR4A2PDK2MEN1KMT2A
SCHEMBL3583643 0.73 ABL1 (0.53) ABL1NR4A2MEN1KMT2ASLC6A4
SCHEMBL27851463 0.73 ABL1 (0.53) ABL1NR4A2MEN1KMT2ASLC6A4
SCHEMBL14605600 0.73 ABL1 (0.53) ABL1NR4A2MEN1KMT2ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0778268-B1 Trifluoromethanesulfinanilide compound and use thereof SUMITOMO CHEMICAL CO (JP) 1999-11-03 EP disclosed
US-5698591-A Trifluoromethanesulfinanilide, process for preparing trifluoromethanesulfonanilide from the same, and a controlling agent formulated from trifluoromethanesulfinanilide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
EP-0778268-A1 Trifluoromethanesulfinanilide compound and use thereof SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-06-11 EP disclosed