Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 8/20 | 0.58 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843057 | 1.00 | CHRNA7 (0.58) | CHRNA7HTR3AUSP30SMYD3CHRM4 | |
| SCHEMBL843467 | 1.00 | CHRNA7 (0.58) | CHRNA7HTR3AUSP30SMYD3CHRM4 | |
| SCHEMBL843707 | 0.92 | CHRNA7 (0.61) | CHRNA7HTR3AUSP30SMYD3CHRM4 | |
| SCHEMBL843708 | 0.92 | CHRNA7 (0.61) | CHRNA7HTR3AUSP30SMYD3CHRM4 | |
| SCHEMBL843933 | 0.88 | CHRNA7 (0.57) | CHRNA7HTR3AUSP30SMYD3CHRM4 | |
| SCHEMBL843865 | 0.88 | CHRNA7 (0.57) | CHRNA7HTR3AUSP30SMYD3CHRM4 | |
| SCHEMBL843159 | 0.88 | CHRNA7 (0.57) | CHRNA7HTR3AUSP30SMYD3CHRM4 | |
| SCHEMBL843864 | 0.88 | CHRNA7 (0.57) | CHRNA7HTR3AUSP30SMYD3CHRM4 | |
| SCHEMBL843385 | 0.84 | CHRNA7 (0.64) | CHRNA7HTR3AUSP30CHRM4 | |
| SCHEMBL844481 | 0.84 | CHRNA7 (0.64) | CHRNA7HTR3AUSP30CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432707-B1 | AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN CO LLC (US) | 2012-03-28 | — | — | EP | disclosed |