Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10350180 | 0.93 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2CYSLTR2 | |
| SCHEMBL9716995 | 0.93 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2CYSLTR2 | |
| SCHEMBL4331860 | 0.93 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2CYSLTR2 | |
| SCHEMBL8092292 | 0.93 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2CYSLTR2 | |
| SCHEMBL9716933 | 0.93 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2CYSLTR2 | |
| SCHEMBL9717006 | 0.93 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2CYSLTR2 | |
| SCHEMBL242465 | 0.93 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2CYSLTR2 | |
| SCHEMBL9402733 | 0.93 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2CYSLTR2 | |
| SCHEMBL4331862 | 0.93 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2CYSLTR2 | |
| SCHEMBL3084631 | 0.93 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5976555-A | EMULSIFIER SYSTEM | JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. (US) | 1999-11-02 | — | — | US | disclosed |