SCHEMBL8431504

SCHEMBL8431504

[CH]=CCCCBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5314595 0.90
SCHEMBL9220322 0.87
SCHEMBL3498191 0.76
SCHEMBL3499333 0.76
SCHEMBL1541496 0.72
SCHEMBL28999194 0.69 TSHR (0.35)
SCHEMBL7853318 0.69
SCHEMBL31706607 0.69 TSHR (0.35)
SCHEMBL3497023 0.66
SCHEMBL291972 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114989142-A Preparation method of pyrazole compound 沈阳万菱生物技术有限公司 2022-09-02 CN claimed
CN-108368069-B Oxazine compound, composition and cured product DIC株式会社 2022-10-14 CN disclosed
CN-114989142-A Preparation method of pyrazole compound 沈阳万菱生物技术有限公司 2022-09-02 CN disclosed
CN-108473642-B Oxazine compound, composition and cured product DIC株式会社 2021-05-07 CN disclosed
CN-108368217-B Oxazine compound, composition and cured product DIC株式会社 2021-05-07 CN disclosed
CN-108368218-B Oxazine compound, composition and cured product DIC株式会社 2020-11-06 CN disclosed
CN-108368216-B Oxazine compound, composition and cured product DIC株式会社 2020-09-18 CN disclosed
CN-105408322-B Terazololine-one compound and application thereof 住友化学株式会社 2019-04-19 CN disclosed
CN-103848846-B Method for preparing benzene thiophene compound 艾尼股份公司 2017-08-25 CN disclosed
CN-104271571-B Tetrazolinone compound and use thereof 住友化学株式会社 2017-07-07 CN disclosed
CN-101778832-A Oxopyrazine derivative and weedicide KUMIAI CHEMICAL INDUSTRY CO 2010-07-14 CN disclosed
CN-101522657-A STAT3/5 activation inhibitor OTSUKA PHARMA CO LTD (JP) 2009-09-02 CN disclosed
CN-101321529-A Diaryl aether derivant as antineoplastic agent OTSUKA PHARMA CO LTD (JP) 2008-12-10 CN disclosed
CN-1993339-A Aromatic compound OTSUKA PHARMA CO LTD (JP) 2007-07-04 CN disclosed
CN-1395578-A Byrido [2,3-d] pyrimidine-2, 7-diamine kinase inhibitors WARNER LAMBERT CO (US) 2003-02-05 CN disclosed
CN-1373763-A Pteridinones and kinase inhibitors WARNER LAMBERT CO (US) 2002-10-09 CN disclosed
US-5942638-A Method of functionalizing polycyclic silicones and the resulting compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1999-08-24 US disclosed
EP-0192242-B1 SUBSTITUTED AMINOPHENYLUREA DERIVATIVES TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-11-07 EP disclosed
US-4803223-A ANTITUMOR AGENTS TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1989-02-07 US disclosed
EP-0192242-A1 Substituted aminophenylurea derivatives TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-08-27 EP disclosed