Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 3/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060033 | 0.81 | TLR7 (0.48) | TLR7TLR8NUDT1KDM4E | |
| SCHEMBL4060026 | 0.81 | TLR7 (0.48) | TLR7TLR8NUDT1KDM4E | |
| SCHEMBL842450 | 0.78 | TLR7 (0.49) | TLR7TLR8NUDT1KDM4EGLA | |
| SCHEMBL5452417 | 0.76 | TLR7 (0.48) | TLR7TLR8NUDT1 | |
| SCHEMBL17181525 | 0.75 | TLR7 (0.53) | TLR7TLR8NUDT1 | |
| SCHEMBL29385735 | 0.75 | TLR7 (0.57) | TLR7TLR8NUDT1 | |
| SCHEMBL4532094 | 0.75 | TLR7 (0.57) | TLR7TLR8NUDT1 | |
| SCHEMBL842116 | 0.73 | TLR7 (0.62) | TLR7TLR8NUDT1 | |
| SCHEMBL22158688 | 0.72 | TLR7 (0.47) | TLR7TLR8NUDT1 | |
| SCHEMBL2059398 | 0.71 | TLR7 (0.46) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143270-B2 | 2-amino 1H-in-imidazo ring systems and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-03-27 | — | — | US | disclosed |