SCHEMBL8432135

SCHEMBL8432135

CCOC(=O)C(=Cc1ccccc1Br)C(=O)OCC

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.66
KMT2A Q03164 6/20 0.66
MAPT P10636 5/20 0.66
LMNA P02545 3/20 0.66
POLB P06746 2/20 0.66
PLIN1 O60240 1/20 0.66
PLIN5 Q00G26 1/20 0.66
ABHD5 Q8WTS1 1/20 0.66
NPSR1 Q6W5P4 2/20 0.58
S1PR4 O95977 1/20 0.58
S1PR1 P21453 1/20 0.58
MAPK1 P28482 1/20 0.58
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
NR1H4 Q96RI1 1/20 0.48
DHODH Q02127 3/20 0.47
GAA P10253 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6220710 0.87 MAPT (0.50) MEN1KMT2AMAPTLMNAPOLB
SCHEMBL6220713 0.87 MAPT (0.50) MEN1KMT2AMAPTLMNAPOLB
SCHEMBL27720032 0.86 MEN1 (0.49) MEN1KMT2AMAPTLMNAPOLB
SCHEMBL27720090 0.86 MEN1 (0.49) MEN1KMT2AMAPTLMNAPOLB
SCHEMBL1676566 0.86 MEN1 (0.53) MEN1KMT2AMAPTLMNAPOLB
SCHEMBL28562987 0.86 MAPT (0.49) MEN1KMT2AMAPTLMNAPOLB
SCHEMBL29015138 0.84 MEN1 (0.48) MEN1KMT2AMAPTLMNAPOLB
SCHEMBL29489368 0.83 MAPT (0.69) MEN1KMT2AMAPTLMNAPOLB
SCHEMBL11781724 0.83 MAPT (0.69) MEN1KMT2AMAPTLMNAPOLB
Benzene SCHEMBL29015144 0.83 MEN1 (0.50) MEN1KMT2AMAPTLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1249312-A Propylene Homopolymer, Propylene Copolymer and Propylene Elastomer MITSUI CHEMICALS INC (JP) 2000-04-05 CN disclosed
US-5942459-A ALUMOXANE-FREE MIXTURE OF TRANSITION METAL METALLOCENE, ORGANOALUMINUM COMPOUND, BORIC ACID-CONTAINING POWDER MITSUBISHI CHEMICAL CORPORATION (JP) 1999-08-24 US disclosed
EP-0728773-B1 Catalysts for olefin polymerization and a process for preparing olefin polymers therewith MITSUBISHI CHEM CORP (JP) 1998-11-04 EP disclosed
EP-0728773-A1 Catalysts for olefin polymerization and a process for preparing olefin polymers therewith MITSUBISHI CHEMICAL CORPORATION (JP) 1996-08-28 EP disclosed
EP-0195097-B1 ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE BEECHAM GROUP PLC (GB) 1987-10-28 EP disclosed
US-4699995-A ANTIALLERGENS BEECHAM GROUP P.L.C. (GB) 1987-10-13 US disclosed
EP-0142145-B1 ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE BEECHAM GROUP PLC (GB) 1987-03-04 EP disclosed
EP-0195097-A1 Arachidonic acid analogues, processes for their preparation and their use in medicine BEECHAM GROUP PLC (GB) 1986-09-24 EP disclosed
EP-0142145-A2 Arachidonic acid analogues, processes for their preparation and their use in medicine BEECHAM GROUP PLC (GB) 1985-05-22 EP disclosed