Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | APAF1 | O14727 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077147 | 0.99 | KMT2A (0.57) | KMT2AMAPTAPAF1ALDH1A1GAA | |
| SCHEMBL1020354 | 0.90 | KMT2A (0.62) | KMT2AMAPTAPAF1ALDH1A1GAA | |
| SCHEMBL6505837 | 0.82 | TDP1 (0.56) | MAPTRAB9ACASP3HDAC3HDAC4 | |
| SCHEMBL14560538 | 0.81 | KMT2A (0.62) | KMT2AMAPTAPAF1ALDH1A1GAA | |
| SCHEMBL9381432 | 0.81 | KMT2A (0.62) | KMT2AMAPTAPAF1ALDH1A1GAA | |
| SCHEMBL1260843 | 0.81 | KMT2A (0.60) | KMT2AMAPTAPAF1ALDH1A1GAA | |
| SCHEMBL997571 | 0.81 | TDP1 (0.58) | KMT2AMEN1ACHECASP3HDAC3 | |
| SCHEMBL31036100 | 0.81 | TDP1 (0.58) | KMT2AMEN1ACHECASP3HDAC3 | |
| SCHEMBL793609 | 0.81 | TDP1 (0.58) | KMT2AMEN1ACHECASP3HDAC3 | |
| SCHEMBL29545568 | 0.81 | TDP1 (0.58) | KMT2AMEN1ACHECASP3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859017-A | PREVENTING OR TREATING ALLERGIES; INHIBITING INTRACELLULAR GENERATION OF PHOSPHATIDIC ACID AND DIACYLGLYCEROL | CELL THERAPEUTICS, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1995026722-A1 | METHOD FOR INHIBITING MAST CELL AND BASOPHIL ACTIVATION | CELL THERAPEUTICS, INC. (US) | 1995-10-12 | — | — | WO | disclosed |