Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8755027 | 0.83 | MAOB (0.68) | FFAR1MAOBMAOASCN9A | |
| Hydrochloric Acid SCHEMBL8755417 | 0.82 | MAOB (0.67) | FFAR1MAOBMAOASCN9A | |
| Hydrochloric Acid SCHEMBL8755428 | 0.82 | MAOB (0.67) | FFAR1MAOBMAOASCN9A | |
| SCHEMBL8431818 | 0.82 | MAOB (0.72) | MAOBMAOASCN9APPARA | |
| SCHEMBL8755053 | 0.78 | FFAR1 (0.59) | FFAR1MAOBMAOASCN9APPARA | |
| SCHEMBL8432192 | 0.76 | FFAR1 (0.57) | FFAR1MAOBMAOASCN9APPARA | |
| SCHEMBL3970941 | 0.76 | FFAR1 (0.57) | FFAR1MAOBMAOASCN9APPARA | |
| SCHEMBL8755044 | 0.76 | FFAR1 (0.60) | FFAR1MAOBMAOASCN9ACDC7 | |
| Hydrochloric Acid SCHEMBL27433224 | 0.75 | FFAR1 (0.59) | FFAR1MAOBMAOASCN9ACDC7 | |
| SCHEMBL6692696 | 0.75 | FFAR1 (0.67) | FFAR1MAOBHDAC4MEF2DNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | disclosed |