Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | HTT | P42858 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.67 |
| ▸ | APEX1 | P27695 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392319 | 0.87 | USP2 (0.77) | USP2KMT2AHTTHPGDTSHR | |
| SCHEMBL10674129 | 0.86 | USP2 (0.75) | USP2KMT2AHTTHPGDTSHR | |
| SCHEMBL8635709 | 0.84 | KMT2A (1.00) | USP2KMT2AHTTHPGDLMNA | |
| SCHEMBL1984940 | 0.84 | KMT2A (1.00) | USP2KMT2AHTTHPGDLMNA | |
| SCHEMBL13161966 | 0.84 | USP2 (0.72) | USP2KMT2AHTTHPGDTSHR | |
| SCHEMBL6987102 | 0.84 | USP2 (0.72) | USP2KMT2AHTTHPGDTSHR | |
| SCHEMBL1399530 | 0.84 | USP2 (0.72) | USP2KMT2AHTTHPGDTSHR | |
| SCHEMBL11625657 | 0.84 | USP2 (0.72) | USP2KMT2AHTTHPGDTSHR | |
| SCHEMBL18477517 | 0.84 | USP2 (0.72) | USP2KMT2AHTTHPGDTSHR | |
| SCHEMBL1161997 | 0.83 | NAMPT (0.75) | USP2KMT2AHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891737-A | ORTHOGONALLY PROTECTED TRIFUNCTIONAL SCAFFOLDS FOR SOLID PHASE SYNTHESIS OF PEPTIDOMIMETIC COMBINATORIAL LIBRARY | ZYMOGENETICS, INC. (US) | 1999-04-06 | — | — | US | disclosed |
| US-5646285-A | ORTHOGONALLY PROTECTED COMPOUNDS | ZYMOGENETICS, INC. (US) | 1997-07-08 | — | — | US | disclosed |