Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432738 | 1.00 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7445549 | 1.00 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8431373 | 0.91 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7403440 | 0.91 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8431376 | 0.91 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8357451 | 0.91 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8357454 | 0.91 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7419473 | 0.86 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8330022 | 0.84 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8330028 | 0.84 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5900417-A | 1,3,3-(Trisubstituted)cyclohexanemonomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-05-04 | — | — | US | disclosed |