Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.47 |
| ▸ | FNTB | P49356 | 15/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297155 | 0.91 | FNTA (0.46) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8387732 | 0.86 | CYP11B1 (0.45) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8387731 | 0.86 | CYP11B1 (0.45) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8387804 | 0.85 | FNTA (0.45) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8495647 | 0.85 | CYP11B1 (0.47) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8499303 | 0.82 | FNTA (0.47) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8499308 | 0.82 | FNTA (0.47) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8501376 | 0.81 | CYP11B1 (0.44) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8501373 | 0.81 | CYP11B1 (0.44) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8498084 | 0.81 | CYP11B1 (0.49) | FNTAFNTBPGGT1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833633-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 1999-03-24 | — | — | EP | claimed |
| EP-0833633-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-04-08 | — | — | EP | claimed |