Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2685181 | 0.96 | CYP3A4 (0.84) | CYP3A4L3MBTL1TSHRCA2FDPS | |
| SCHEMBL3331725 | 0.94 | CYP3A4 (0.69) | CYP3A4L3MBTL1TSHRCA2CA12 | |
| SCHEMBL2947905 | 0.91 | CYP3A4 (0.63) | CYP3A4L3MBTL1TSHRCA2CA12 | |
| SCHEMBL1986718 | 0.90 | CYP3A4 (0.75) | CYP3A4L3MBTL1TSHRFDPSSMPD1 | |
| SCHEMBL8564175 | 0.88 | CYP3A4 (0.71) | CYP3A4L3MBTL1TSHRFDPSSMPD1 | |
| SCHEMBL10901321 | 0.88 | CYP3A4 (0.71) | CYP3A4L3MBTL1TSHRFDPSSMPD1 | |
| SCHEMBL7942552 | 0.88 | CYP3A4 (0.71) | CYP3A4L3MBTL1TSHRFDPSSMPD1 | |
| SCHEMBL10902137 | 0.88 | CYP3A4 (0.71) | CYP3A4L3MBTL1TSHRFDPSSMPD1 | |
| SCHEMBL19362857 | 0.88 | CYP3A4 (1.00) | CYP3A4L3MBTL1TSHRCA2FDPS | |
| SCHEMBL35485 | 0.88 | CYP3A4 (1.00) | CYP3A4L3MBTL1TSHRCA2FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922654-A | TWO OR MORE ORGANOMETALLIC COMPOUNDS WHERE THE METAL IS A TRANSITION METAL OR SEMIMETAL, OR ZINC; FOR EXAMPLE, ZINC DIALKYLDITHIOPHOSPHATE, OR NICKEL DIALKYLDITHIOCARBAMATE; HIGHER LOAD BEARING PROPERTIES, HIGH TEMPERATURE PERFORMANCE | NSK LTD. (JP) | 1999-07-13 | — | — | US | disclosed |