⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8434662 | 0.98 | — | — | |
| SCHEMBL8430712 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL9157842 | 0.71 | MEN1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL8434659 | 0.71 | — | — | |
| SCHEMBL8433504 | 0.70 | — | — | |
| SCHEMBL20816370 | 0.70 | TSHR (0.33) | — | |
| Hydrochloric Acid SCHEMBL8433444 | 0.66 | MAPK1 (0.32) | — | |
| SCHEMBL453673 | 0.60 | — | — | |
| SCHEMBL10433647 | 0.58 | — | — | |
| SCHEMBL14577554 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981545-A | FOR USE IN THE TREATMENT AND/OR PROPHYLAXIS OF DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1999-11-09 | — | — | US | claimed |
| EP-0427390-B1 | Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1996-03-27 | — | — | EP | claimed |
| EP-0427390-A2 | Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1991-05-15 | — | — | EP | claimed |