Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 12/20 | 0.49 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.42 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GALK1 | P51570 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432743 | 1.00 | TLR4 (0.49) | TLR4LGALS8SYNJ2KDM4EABL1 | |
| SCHEMBL8432746 | 1.00 | TLR4 (0.49) | TLR4LGALS8SYNJ2KDM4EABL1 | |
| SCHEMBL8436288 | 0.96 | TLR4 (0.54) | TLR4 | |
| SCHEMBL8431958 | 0.96 | TLR4 (0.54) | TLR4 | |
| SCHEMBL10418883 | 0.96 | TLR4 (0.54) | TLR4MCHR1 | |
| SCHEMBL8431429 | 0.94 | TLR4 (0.53) | TLR4LGALS8MCHR1 | |
| SCHEMBL6807622 | 0.93 | TLR4 (0.57) | TLR4LGALS8 | |
| SCHEMBL6800991 | 0.93 | TLR4 (0.57) | TLR4LGALS8 | |
| SCHEMBL6795483 | 0.93 | TLR4 (0.57) | TLR4LGALS8 | |
| SCHEMBL6807623 | 0.93 | TLR4 (0.57) | TLR4LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36385-E | TREATMENT OF TUMORS, ENHANCING IMMUNITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |