Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434853 | 1.00 | MAOB (0.41) | MAOBMAOAPSMD14HSP90AA1MMP2 | |
| SCHEMBL8434871 | 1.00 | MAOB (0.41) | MAOBMAOAPSMD14HSP90AA1MMP2 | |
| SCHEMBL8977228 | 1.00 | MAOB (0.41) | MAOBMAOAPSMD14HSP90AA1MMP2 | |
| SCHEMBL8434869 | 1.00 | MAOB (0.41) | MAOBMAOAPSMD14HSP90AA1MMP2 | |
| SCHEMBL8432739 | 0.96 | MAOB (0.42) | MAOBMAOA | |
| SCHEMBL8432742 | 0.96 | MAOB (0.42) | MAOBMAOA | |
| SCHEMBL8432734 | 0.91 | MAOB (0.44) | MAOBMAOA | |
| SCHEMBL8432737 | 0.91 | MAOB (0.44) | MAOBMAOA | |
| SCHEMBL8977329 | 0.91 | MAOB (0.44) | MAOBMAOA | |
| SCHEMBL7757734 | 0.89 | MAOB (0.49) | MAOBMAOAPSMD14HSP90AA1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665232-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5498737-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0665232-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-08-02 | — | — | EP | disclosed |