Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 5/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 7/20 | 0.38 |
| ▸ | USP1 | O94782 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435392 | 0.85 | TYMS (0.52) | PNPTLR7TYMSKDM4EALDH1A1 | |
| SCHEMBL8434466 | 0.84 | TYMS (0.53) | PNPTLR7DHFRTYMSMEN1 | |
| SCHEMBL8439184 | 0.84 | PNP (0.61) | PNPTLR7TYMSKDM4EALDH1A1 | |
| SCHEMBL338656 | 0.77 | PNP (0.46) | PNPTLR7TYMSALDH1A1PKM | |
| SCHEMBL22040457 | 0.77 | PNP (0.55) | PNPTLR7DHFRTYMSKDM4E | |
| SCHEMBL13851087 | 0.76 | HPGD (0.51) | PNPTLR7HPGD | |
| SCHEMBL8440066 | 0.72 | PNP (0.41) | PNPTLR7 | |
| SCHEMBL339228 | 0.70 | TLR7 (0.47) | TLR7MEN1KMT2A | |
| SCHEMBL339348 | 0.69 | TLR7 (0.38) | TLR7 | |
| SCHEMBL6977181 | 0.69 | TLR7 (0.38) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994321-A | Antiviral guanine analogs | ARONEX PHARMACEUTICALS, INC. (US) | 1999-11-30 | — | — | US | disclosed |