SCHEMBL8436366

SCHEMBL8436366

[CH2]C(=O)NCC(C)(C)CC

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8436372 0.78 KDM4E (0.39) SMN1; SMN2HSD17B10TSHR
SCHEMBL6729276 0.78 SMN1; SMN2 (0.38) SMN1; SMN2HSD17B10TSHR
SCHEMBL6729273 0.78 SMN1; SMN2 (0.38) SMN1; SMN2HSD17B10TSHR
SCHEMBL8438042 0.77 SMN1; SMN2 (0.34) SMN1; SMN2HSD17B10TSHR
SCHEMBL771089 0.77
SCHEMBL9768528 0.76 SMN1; SMN2 (0.36) SMN1; SMN2HSD17B10TSHR
SCHEMBL20218595 0.76 SMN1; SMN2 (0.36) SMN1; SMN2HSD17B10TSHR
SCHEMBL12847744 0.76 MEN1 (0.46) SMN1; SMN2HSD17B10TSHR
SCHEMBL20216160 0.76 SMN1; SMN2 (0.37) SMN1; SMN2HSD17B10
SCHEMBL12314771 0.76 TSHR (0.48) SMN1; SMN2HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0777658-B1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AG (DE) 1999-12-15 EP disclosed
US-5885934-A HERBICIDES OR FOR THE DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 1999-03-23 US disclosed
EP-0777658-A1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AKTIENGESELLSCHAFT (DE) 1997-06-11 EP disclosed
WO-1996005179-A1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AKTIENGESELLSCHAFT (DE) 1996-02-22 WO disclosed