Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | FPR1 | P21462 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519327 | 0.87 | HPGD (0.71) | NPC1RAB9AHPGDTP53CA1 | |
| SCHEMBL10522363 | 0.87 | NPC1 (0.50) | NPC1RAB9AHPGDTP53CA1 | |
| SCHEMBL10516550 | 0.85 | HPGD (0.59) | NPC1RAB9AHPGDTP53CA1 | |
| SCHEMBL10515781 | 0.85 | CA1 (0.42) | NPC1RAB9AHPGDTP53CA1 | |
| SCHEMBL10521431 | 0.85 | NPC1 (0.48) | NPC1RAB9AHPGDTP53CA1 | |
| SCHEMBL10513336 | 0.83 | MAPT (0.40) | NPC1RAB9AHPGDTP53CA1 | |
| SCHEMBL10555587 | 0.83 | HPGD (0.54) | NPC1RAB9AHPGDTP53CA1 | |
| SCHEMBL2743092 | 0.82 | NPC1 (0.75) | NPC1RAB9AHPGDTP53POLB | |
| SCHEMBL10516070 | 0.82 | NPC1 (0.53) | NPC1RAB9AHPGDTP53CA1 | |
| SCHEMBL9600739 | 0.82 | HPGD (0.50) | NPC1RAB9AHPGDTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886176-A | Process for preparing sulphonylurea salts | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
| EP-0559044-A1 | Process for the preparation of sulfonylurea salts | BAYER AG (DE) | 1993-09-08 | — | — | EP | disclosed |
| EP-0318602-B1 | PYRAZOLESULFONAMIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND HERBICIDE CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-4881965-A | CONTROLLING WILD OATS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-21 | — | — | US | disclosed |
| EP-0318602-A1 | Pyrazolesulfonamide derivative, process for its production and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |
| CN-86100911-A | The preparation method of pyrazoles sulfone amide derivative and the weedicide that contains this kind derivative | — | 1986-09-24 | — | — | CN | disclosed |