Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446636 | 0.82 | MAOB (0.56) | MAOBMRGPRX4CYP11B1CYP11B2IMPDH2 | |
| SCHEMBL16355763 | 0.79 | MAOB (0.54) | MAOBMRGPRX4ALOX5 | |
| SCHEMBL12722195 | 0.76 | MRGPRX4 (0.51) | MAOBMRGPRX4CYP11B1CYP11B2 | |
| SCHEMBL12818915 | 0.76 | MAOB (0.43) | MAOB | |
| SCHEMBL29879322 | 0.76 | MAOB (0.43) | MAOB | |
| SCHEMBL9235297 | 0.75 | MAOB (0.61) | MAOBALOX5NR4A2 | |
| SCHEMBL7404465 | 0.75 | MAOB (0.63) | MAOBMRGPRX4IMPDH2NR4A2 | |
| SCHEMBL4260225 | 0.75 | MAOB (0.77) | MAOBMRGPRX4IMPDH2ALOX5NR4A2 | |
| SCHEMBL3648539 | 0.74 | MAOB (1.00) | MAOBMRGPRX4IMPDH2ALOX5NR4A2 | |
| SCHEMBL24379122 | 0.74 | MAOB (0.62) | MAOBMRGPRX4IMPDH2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969146-A | MONOAMINE OXIDASE INHIBITORS | SYNTHELABO (FR) | 1999-10-19 | — | — | US | disclosed |