Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436863 | 1.00 | CNR1 (0.35) | CNR1SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL8436860 | 1.00 | CNR1 (0.35) | CNR1SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL8042959 | 0.91 | SLC6A2 (0.38) | CNR1SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL8019283 | 0.90 | CYP17A1 (0.37) | CNR1MAOBGPR84 | |
| SCHEMBL8019285 | 0.90 | CYP17A1 (0.37) | CNR1MAOBGPR84 | |
| SCHEMBL8019284 | 0.90 | CYP17A1 (0.37) | CNR1MAOBGPR84 | |
| SCHEMBL21581480 | 0.88 | SLC6A2 (0.41) | CNR1SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL21581481 | 0.87 | SLC6A2 (0.40) | CNR1SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL8432747 | 0.86 | — | — | |
| SCHEMBL8432749 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665232-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5498737-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0665232-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-08-02 | — | — | EP | disclosed |