SCHEMBL8437289

SCHEMBL8437289

C=CCCCC[Si](Cl)(Cl)CC

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
ALDH1A1 P00352 2/20 0.44
LMNA P02545 1/20 0.31
ABCC4 O15439 1/20 0.31
MAPT P10636 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31414055 0.98 TSHR (0.50) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL28492066 0.98 TSHR (0.50) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL6037392 0.98 TSHR (0.50) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL28350276 0.98 TSHR (0.50) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL28491279 0.98 TSHR (0.50) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL3896306 0.93 TSHR (0.46) TSHRALDH1A1
SCHEMBL28395078 0.85 TSHR (0.42) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL388316 0.83
SCHEMBL31255771 0.83 TSHR (0.46) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL31255803 0.83 TSHR (0.46) TSHRALDH1A1LMNAABCC4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036997-A Modified polyolefin catalyst and preparation method and application thereof 中国石油天然气股份有限公司 2026-05-15 CN claimed
CN-116199813-B Long chain branched polypropylene and preparation method thereof 中国科学院化学研究所 2025-02-11 CN claimed
CN-118063658-A Polybutene-1 and process for preparing same 中国科学院化学研究所 2024-05-24 CN claimed
CN-116199813-A Long chain branched polypropylene and preparation method thereof 中国科学院化学研究所 2023-06-02 CN claimed
CN-112143114-B Long-chain branched polypropylene impact copolymer and preparation method thereof 中国科学院化学研究所 2021-10-22 CN claimed
CN-112143113-B Long-chain branched polypropylene impact copolymer and preparation method thereof 中国科学院化学研究所 2021-09-21 CN claimed
CN-112142897-B Application of organosilane in preparation of linear low density polyethylene, linear low density polyethylene and preparation method and application thereof 中国科学院化学研究所 2021-07-27 CN claimed
CN-112142894-B Application of organosilane in preparation of high-density polyethylene, high-density polyethylene and preparation method and application thereof 中国科学院化学研究所 2021-05-25 CN claimed
CN-112143113-A Long-chain branched polypropylene impact copolymer and preparation method thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-112143114-A Long-chain branched polypropylene impact copolymer and preparation method thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-112142895-A Application of organosilane, random copolymerization polypropylene and preparation method thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-112142894-A Application of organosilane in preparation of high-density polyethylene, high-density polyethylene and preparation method and application thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-112142897-A Application of organosilane in preparation of linear low density polyethylene, linear low density polyethylene and preparation method and application thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-108659151-B Application of organosilane, polypropylene and preparation method of polypropylene 中国科学院化学研究所 2020-01-10 CN claimed
CN-108659151-A A kind of application of organosilan and polypropylene and preparation method thereof 中国科学院化学研究所 2018-10-16 CN claimed
CN-119978203-A Polyolefin elastomer material and preparation method thereof 浙江大学宁波“五位一体”校区教育发展中心 2025-05-13 CN disclosed
CN-116199813-B Long chain branched polypropylene and preparation method thereof 中国科学院化学研究所 2025-02-11 CN disclosed
CN-108659151-A A kind of application of organosilan and polypropylene and preparation method thereof 中国科学院化学研究所 2018-10-16 CN disclosed
US-5985462-A COATINGS, RELEASE AGENTS; HYDROSILATION; CATALYSIS WACKER-CHEMIE GMBH (DE) 1999-11-16 US disclosed
EP-0829518-A1 Crosslinkable compositions containing silicon compounds having hydrogen atoms bound to silicon Wacker-Chemie GmbH (DE) 1998-03-18 EP disclosed