Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156168 | 1.00 | CYP2D6 (0.45) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3375896 | 0.90 | CYP2D6 (0.41) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL31165203 | 0.90 | CYP2D6 (0.41) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL16320670 | 0.90 | CYP2D6 (0.41) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1260626 | 0.90 | CYP2D6 (0.41) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL16320897 | 0.90 | CYP2D6 (0.41) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6154559 | 0.87 | CYP2D6 (0.50) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1135909 | 0.85 | CYP2D6 (0.41) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3439226 | 0.85 | CYP2D6 (0.41) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL29223109 | 0.85 | CYP2D6 (0.41) | CYP2D6HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288994-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS | Chisso Corporation (JP) | 1992-07-22 | — | — | EP | claimed |
| EP-0208662-B1 | PROCESS FOR MANUFACTURING R(-)-NORCARNITINE TERT-BUTYL ESTER | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-12-14 | — | — | EP | claimed |
| EP-0288994-A2 | Process for producing optically active compounds | Chisso Corporation (JP) | 1988-11-02 | — | — | EP | claimed |
| CN-111172124-B | Carbonyl reductase mutant and preparation thereofR) Application of (E) -4-chloro-3-hydroxy-butyrate | 复旦大学 | 2022-07-22 | — | — | CN | disclosed |
| US-10961515-B1 | Carbonyl reductase variant and its use in preparation of (R)-4-chloro-3-hydroxybutyrate | FUDAN UNIVERSITY (CN) | 2021-03-30 | — | — | US | disclosed |
| CN-111172124-A | Carbonyl reductase mutant and application thereof in preparation of (R) -4-chloro-3-hydroxy-butyrate | 复旦大学 | 2020-05-19 | — | — | CN | disclosed |
| EP-0606899-B1 | Processes for production of optically active 4-halo-3-hydroxybutyric acid esters | DAICEL CHEM (JP) | 1999-12-15 | — | — | EP | disclosed |
| EP-0288994-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS | Chisso Corporation (JP) | 1992-07-22 | — | — | EP | disclosed |
| US-4962031-A | SPECIFIC COMPOUNDS HAVING HYDROXYL GROUPS REACTED WITH ESTERS IN PRESENCE OF HYDROLASES | CHISSO CORPORATION (JP) | 1990-10-09 | — | — | US | disclosed |
| US-4902604-A | CATIONIC AZULENE DERIVATIVE; PRINTING PLATES, RESISTS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0208662-B1 | PROCESS FOR MANUFACTURING R(-)-NORCARNITINE TERT-BUTYL ESTER | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-12-14 | — | — | EP | disclosed |
| EP-0288994-A2 | Process for producing optically active compounds | Chisso Corporation (JP) | 1988-11-02 | — | — | EP | disclosed |
| US-4710468-A | FROM OPTICALLY ACTIVE SUBSTITUTED HYDROXYBUTYRIC ACID DERIVATIVES WITH OXIDOREDUCTASE | SIGMA-TAU INDUSTRIE PHARMACEUTICHE RIUNITE S.P.A. (IT) | 1987-12-01 | — | — | US | disclosed |
| EP-0208662-A1 | Process for manufacturing r(-)-norcarnitine tert-butyl ester | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1987-01-14 | — | — | EP | disclosed |