SCHEMBL8438323

SCHEMBL8438323

O=S(=O)(F)C(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19812179 0.81 KDM4E (0.38) KDM4ETSHRTDP1
Lithium Ion SCHEMBL19812137 0.81 KDM4E (0.38) KDM4ETSHRTDP1
Potassium Ion SCHEMBL19812202 0.81 KDM4E (0.38) KDM4ETSHRTDP1
SCHEMBL19810918 0.78 KDM4E (0.43) KDM4ETSHRTDP1
SCHEMBL28635359 0.76 KDM4E (0.42) KDM4ETSHRTDP1
Potassium Ion SCHEMBL19811192 0.76 KDM4E (0.33) KDM4ETSHRTDP1
SCHEMBL19811551 0.76 KDM4E (0.33) KDM4ETSHRTDP1
Lithium Ion SCHEMBL19810983 0.76 KDM4E (0.33) KDM4ETSHRTDP1
Ammonia Solution, Strong SCHEMBL19811927 0.76 KDM4E (0.42) KDM4ETSHRTDP1
Lithium Ion SCHEMBL19811321 0.75 TSHR (0.32) KDM4ETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0966459-A1 PROCESS FOR PREPARING FLUORINATED BETA-SULTONES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-12-29 EP claimed
WO-1998035953-A1 PROCESS FOR PREPARING FLUORINATED BETA-SULTONES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-08-20 WO claimed
US-5723630-A REACTION OF FLUORINATED OLEFIN WITH OLEUM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-03 US claimed
EP-0966459-A1 PROCESS FOR PREPARING FLUORINATED BETA-SULTONES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-12-29 EP disclosed
WO-1998035953-A1 PROCESS FOR PREPARING FLUORINATED BETA-SULTONES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-08-20 WO disclosed
US-5723630-A REACTION OF FLUORINATED OLEFIN WITH OLEUM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-03 US disclosed